Lumbar Puncture (LP)

As part of some of our studies, you may have the option to participate in a lumbar puncture (also known as a spinal tap). By participating in this procedure you are providing us a small amount of your spinal fluid so that we may test it for biomarkers of Alzheimer’s disease (AD). These markers may one day help us to prevent or treat AD.

A lumbar puncture involves placing a needle between the bones of the lower back, below the end of the spinal cord, to draw the fluid known as cerebrospinal fluid or CSF. This fluid flows around the spinal cord and the brain.

The purpose of the lumbar puncture for research is to evaluate how various proteins and substances found in the brain and fluid surrounding the brain and spinal cord affect a person’s risk of getting Alzheimer’s disease or having the disease progress.