The purpose of this study is to collect brain scans and blood samples that will provide information about the brain’s waste clearance system. Researchers will evaluate applications of this knowledge to neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease. The study aims to shed light on the unique physiology of the systems behind the brain’s clearance mechanism as a function of both sexual dimorphism and age.
Who can participate?
We are seeking individuals in the age ranges of 18-35 or 55+ years who are able to participate in an evening MRI scan.
What will happen in this study?
This study consists of two in person visits to the Waisman Center within one month. One visit will include a blood draw, answering questionnaires and a cognitive testing session. The other visit will be an evening MRI scanning session. Participants will be asked to keep a sleep diary and wear a wrist-based sleep monitoring device for seven days prior to the MRI scan.
Procedure Schedule
| Visit A at Waisman Center | Before Visit B | Visit B at Waisman Center |
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Will I be paid for participating in this study?
Yes, you will be paid for participating.
- $30 for a blood sample
- $30 for completing the cognitive testing and questionnaires
- $30 for completing the 7-day at-home sleep diary and monitoring
- $150 for the evening MRI scanner session
The maximum payment for completing all parts of the study is $240.
How can I participate in this study?
If you are interested in being in this study, please complete this participation survey.
Questions?
Contact the study team by emailing brainsleep@waisman.wisc.edu or calling (608) 516-3232.
Study Co-Principal Investigators
