Open Studies

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Actively Recruiting Studies

If you are interested in learning more about any of the following studies at the Wisconsin Alzheimer's Disease Research Center, please contact the Study Coordinator listed.Color

Alzheimer's Disease Research Center Registry (Clinical Core Study)

People who join this study attend a yearly visit in which their memory and thinking abilities are evaluated. They also participate in other ADRC-affiliated studies. Interested volunteers may join this important registry if they can attend a yearly visit with a study partner and either have MCI or are healthy, 45 to 65 years old, and have no parents with Alzheimer's.

Currently recruiting people with mild cognitive impairment (MCI), and healthy people aged 45 - 65, with no parental history of Alzheimer's disease.

If you are interested in participating or learning more about the study, please contact the coordinator, Zak Zugin at (608) 265-6347.

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EXERT Study

The EXERT study is looking for participants to help researchers identify the right dose of exercise for people with mild memory problems. Participants who take part in this study, will complete screening procedures on the phone and in the clinic. Once enrolled, participants will complete up to 10 outpatient visits to our research centers over a 20 month period. Clinic visits will include physical exam, blood collection, cognitive testing, brain imaging and optional lumbar puncture.

Participants must be 65-89 years old with mild memory loss or diagnosed with Mild Cognitive Impairment, in otherwise good health, have no metal in the body and must be able to exercise at a participating local YMCA 4 times per week for 18 months (duration of study). Participants must also have someone who knows them well and who would be willing to come to the clinic to answer questions about the participant. Eligible adults must be willing to participate in either the stretching/balance/range-of-motion group or the aerobic group.

If you are interested in participating or learning more about the study, please contact Beth Jeanes via email at emjeanes@medicine.wisc.edu or call (608) 265-5752.

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Predicting Alzheimer's from Metabolic Measures and Sleep (PAMMS)

PAMMS evaluates brain changes over time that might be related to developing AD by examining metabolic measures and sleep to see how they affect the brain. Prerequisite: Must be a member of the Clinical Core Study.

Currently recruiting people with healthy memory aged 40 and older, either with or without a parent who has/had Alzheimer's disease.

If you are interested in participating or learning more about the study, please contact the coordinator, Nancy Davenport at (608) 262-9442.

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Solanezumab Clinical Trial for Those with Preclinical Memory Complaints (A4)

This clinical trial examines the effects of Solanezumab in patients with preclinical memory complaints, but who have not been diagnosed with AD dementia. Volunteers are asked to come to the UW Hospital once a month for 3 years. Interested people may be eligible if they are between 65 and 85 years old and have a study partner who can attend the initial visit and one annual visit.

Currently recruiting people aged 65 to 85 years old with healthy memory.

If you are interested in participating or learning more about the study, please contact the coordinator, Ben Farral at (608) 256-1901, x11640.

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Brain Amyloid and Vascular Effects of Eicosapentaenoic Acid (BRAVE-EPA)

The purpose of this research study is to evaluate if EPA, an omega-3 fatty acid, improves biomarkers of Alzheimer's Disease, and thinking abilitites in middle-aged, cognitively healthy Veterans at risk for this common form of dementia.

We are looking for veterans aged 50-70 years old with normal memory and thinking abilities who have a parent with Alzheimer's disease.  The study requires 9 visits spread over 18 months at the William S. Middleton Memorial Veterans Hospital and the University of Wisconsin in Madison, WI.

If you are interested in participating or learning more about the study, please contact the coordinator, Elena Beckman at (608) 256-1901 ext.11199 or email elena.beckman@va.gov

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Audiology Study

The study investigates the effect of aging and age-related hearing loss on auditory function. The purpose of this study is to find neurophysiological evidence of age-related reduction in the ability to understand speech especially when noise is present.

We are looking for people aged 56 and older with normal hearing, no history of ear surgery, neurological disorders, or cognitive problems. The study requires 3-4 sessions and each session takes 4 hours. You will get paid $10 hourly.  

If you are interested in participating or learning more about the study, please contact the coordinator, call So Park at (858) 525-5057.

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Audiology Study: Detecting Hidden Hearing Loss

This study is being undertaken to help us understand why elderly individuals often experience difficulty understanding speech in noisy situations. 

To qualify for this study, volunteers must be adults age 45 and older with normal hearing, no diagnosis of cognitive impairment or neurological disease. Study participation will require 2-3 visits and each visit will last 1-2 hours.  You will be compensated $10 per hour.

If you have questions or would like to get involved, please contact the coordinator, please contact Jungmee Lee at 520-245-4674 or Jlee632@wisc.edu.

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Join the Wisconsin ADRC Registry

New studies start frequently at the Wisconsin ADRC, and we're looking for men and women volunteers. In order to match interested persons with future studies, the Wisconsin ADRC has created a research database—the Wisconsin ADRC Registry—to hold the names and eligibility information of potential volunteers. When new studies become available, we will use the Wisconsin ADRC Registry to identify persons who may qualify for the new opportunity.

As the future holds limitless possibilities for clinical trial developments, anyone who is interested in contributing to the advancement of memory research may join the Wisconsin ADRC Registry. You do not have to be experiencing memory problems or have a memory diagnosis to join the Registry. Persons with or without memory problems, regardless of family history, may join. Also, joining the Wisconsin ADRC Registry does not commit you to participating in future studies. If you are contacted about a new study, you may decline to participate in that study and still remain in the Registry to receive information about other future studies.

To join the Registry, you will be asked to complete a phone questionnaire that will review your personal and family medical history, your medication use, and if present, your current memory symptoms in detail. Wisconsin ADRC staff may contact you approximately once annually to verify that your medical history and medication information remain up-to-date.                                                                                                                                                                                           --updated 5/15/2017