Dementia Matters

About the Host

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Dr. Nathaniel Chin is host of Dementia Matters. He is a geriatrician, memory clinic doctor, and medical director for the Wisconsin Alzheimer's Disease Research Center. His father's diagnosis with early onset Alzheimer’s disease inspired him to pursue a career as a geriatrician and scientist focused on dementia prevention, especially in regard to Alzheimer's disease.

Dementia Matters is a podcast from the Wisconsin Alzheimer’s Disease Research Center. Host Dr. Nathaniel Chin interviews research and caregiving experts and brings listeners the latest Alzheimer's disease headlines, research news, and caregiver resources.

COVID-19 Special Series — Dementia Matters adjusted its focus for an eight-week special series that addressed important issues affecting those with cognitive impairment, caregivers, and the community at large during this COVID-19 coronavirus pandemic. Listen to episodes here.

Three Ways to Listen

You can listen to episodes through our website or subscribe to Dementia Matters through ApplePodcasts, Spotify, Podbean, Stitcher, or Google Play Music.

If you're in Madison, listen to Dementia Matters on the radio at 102.9 WMUU-LP, Fridays at 4:00 p.m., or stream online.

Contact Us

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Email your questions and episode suggestions to dementiamatters@medicine.wisc.edu.

Audio Editor: Bashir Aden

Producer: Rebecca Wasieleski

COVID-19 Special Series Producer: Bonnie Nuttkinson

Recent Episodes

On October 27th, the NBC drama series This Is Us will return for a fifth season. An integral storyline in the show is the diagnosis of one of the main characters, Rebecca Pearson, with Mild Cognitive impairment (MCI). In this bonus episode, our host Dr. Chin helps define MCI and its potential causes and misconceptions.

Episode Topics:

  • What is Mild Cognitive Impairment? 1:37
  • Difference between MCI and Dementia: 3:29
  • Potential causes for MCI: 4:40

As intermittent fasting has risen in popularity over the last decade, researchers have been exploring its long-term effects on physical health. Dr. Mark Mattson joins to discuss his research on metabolic switching, caloric restrictions, and the cognitive benefits from intermittent fasting. Guest: Mark P. Mattson, PhD, Johns Hopkins University School of Medicine, Department of Neurology

Episode Topics:

  • Defining Intermittent fasting: 1:08
  • How long does it take for a metabolic switch? 2:02
  • How is this process different from normal dietary recommendations? 3:44
  • What did you find in your research on the effects of intermittent fasting on health? 5:36
  • Are there cognitive benefits to intermittent fasting? 8:12
  • Can intermittent fasting and caloric restrictions improve the brain’s health? 9:49
  • How does our modern lifestyles affect our brain and overall health? 16:07
  • Is there any evidence that one way of intermittent fasting is better?17:54
  • Are there any long-term consequences of intermittent fasting? 20:30
  • What do you do in your life to improve your brain health? 22:39

Aerobic exercise is often a recommendation for maintaining cognitive well-being, however its true connections to brain health are still being investigated to learn its effects on Alzheimer’s disease. Wisconsin ADRC exercise physiologist and researcher Max Gaitán joins the podcast to discuss the recent pilot study “Protocol of Aerobic Exercise and Cognitive Health (REACH)” and the study’s future research into the impact of aerobic exercise on brain health. Guest: Max Gaitán, MEd, Research Specialist, University of Wisconsin School of Medicine and Public Health Department of Medicine

Episode topics:

  • What were the goals for the REACH study? 1:56
  • Was it difficult to recruit participants for the study? 3:18
  • What else did you learn from your participants?  4:22
  • Did you see any issues with retention in participants? 5:06
  • What were the results of the study? 5:42
  • What does improved glucose metabolism in the brain mean? 6:57
  • Does exercise improve the health of the brain cells? 7:43
  • What are the goals of studying metabolomics? 8:55 
  • What did you define as usual physical activity? 9:47
  • How were the exercise targets chosen? 10:38
  • Are there studies researching high intensity interval training? 12:39

 

Human factors engineering is the study and design of interactive systems, tools and technologies to best assist individuals in need. We are joined by Nicole Werner, PhD, an engineer working on a mobile technology to serve the lives of informal caregivers. Guest: Nicole Werner, PhD, Harvey D. Spangler Assistant Professor in the Department of Industrial and Systems Engineering, College of Engineering, University of Wisconsin-Madison

Episode topics:

  • Explanation of the field of human factors engineering: 1:05
  • The challenges of informal caregiving: 2:22
  • What are some useful user friendly features for the app? 5:32
  • How is the app being tested and improved? 11:38
  • How do you know when the app will be ready for launch? 14:15
  • Does your lab work with other technology tools for individuals with dementia and their caregivers? 15:55
  • As consumers, what are the essential features that we should look for in technology assistance?: 18:10
  • Have you encountered any tools you’ve found helpful? 20:07
  • What have you learned about caregiving in your work? 22:55

Almost two-thirds of Americans with Alzheimer’s disease are women. In the Alzheimer’s disease research field, there is an interest in understanding the sex-specific differences in the risk and development of this disease. Dr. Michelle Mielke joins to discuss some of these differences as well as how pregnancy and menopause might affect cognition. Guest: Michelle Mielke, PhD, Mayo Clinic Rochester

Episode Topics:

  • What are the sex differences in the development of dementia? 4:09
  • What are explanations for these differences? 7:57
  • What role does pregnancy and menopause play in the development of cognitive disorders? 10:09 
  • Could menopausal hormone replacement therapy affect the cognitive development of dementia in individuals? 14:32
  • Are there sex differences in the genetic risk of APOE? 21:30
  • What do you do in your personal life to maintain brain health? 24:31

A recent study from researchers at the University of Wisconsin School of Medicine and Public Health found that people who lived in the most disadvantaged neighborhoods were about twice as likely to have Alzheimer’s disease-related brain changes at autopsy than people who lived in the wealthiest neighborhoods. One of the authors joins the podcast to discuss the research findings, the methodology behind the study, and future research directions. Guest: Ryan Powell, PhD, University of Wisconsin School of Medicine and Public Health Department of Medicine

 

Episode Topics:

  • What are social determinants of health? 1:30
  • What is the Area Deprivation Index? 3:28
  • What did your study investigate? 7:24
  • What did you learn from your study of brain autopsy results? 8:49
  • How do you think social factors interact with brain changes? 11:10
  • Why is access to Alzheimer’s Disease Research Centers important? 13:35
  • What is the next step for your research? 16:44
  • As a society, how can we slow the development of Alzheimer’s disease? 20:33

After serving as the primary caregiver for his wife for 11 years, Dr. Arthur Kleinman shares the unexpected experiences, difficulties and lessons that he faced. His book, The Soul of Care: The Moral Education of a Husband and a Doctor, chronicles the emotional and physical journey as a caregiver for a loved one with Alzheimer’s disease. Guest: Arthur Kleinman, MD, professor of medical anthropology and cross-cultural psychiatry, Harvard University

 

Episode Topics:

  • Do you believe caregiving and empathy can be taught? 1:25
  • Unexpected experiences as a caregiver: 3:34
  • How do you communicate to your loved ones you need help with caregiving? 10:22
  • Differences between “illness” and “disease”: 20:38
  • Why is important for the community to welcome individuals with memory loss? 27:06

Research data collected from participants around the world has grown our understanding of genetic risk for Alzheimer’s disease. Guest Jessica Langbaum, PhD, is the co-director of the Alzheimer’s Prevention Initiative at Banner Alzheimer’s Institute, which conducts clinical trials in people at high risk for developing Alzheimer’s disease. Langbaum discusses some recent findings in genetic predisposition for Alzheimer’s disease, the psychological consequences of learning one’s risk, and testing interventions to delay or prevent the onset of symptoms. Guest: Jessica Langbaum, PhD, Banner Alzheimer’s Institute

Episode Topics:

  • What is the Alzheimer’s Prevention Initiative? 3:44
  • What is the difference between the APOE gene and the presenilin gene? 6:07
  • How are you approaching disclosure of genetic risk to participants? 12:15
  • What kind of responses have you received from participants who were told about their genetic risk? 15:32
  • What would you recommend to an individual interested in learning their genetic risk? 22:19
  • What are your recommendations for preventing dementia? 24:25
  • What is the GeneMatch program? 26:35 
  • How can individuals find a study to volunteer for? 29:48
  • What is the most feasible form of therapy for dementia? 31:06

A recent study showed that research participants in the most highly disadvantaged neighborhoods had smaller hippocampal areas compared to research participants in more advantaged neighborhoods. The study’s first author explains the results and the tools researchers used to measure neighborhood disadvantage. Guest: Jack Hunt, PhD, University of Wisconsin School of Medicine and Public Health Medical Scientist Training Program

Episode Topics:

  • Association between neighborhood and brain structures: 1:52
  • Study findings: 4:01
  • Defining neighborhood disadvantage: 4:57
  • Who were the research participants involved in the study? 5:42
  • Why did you study the hippocampus in your research? 6:10
  • Related cardiovascular factors: 8:20
  • Using the Neighborhood Atlas to find neighborhood advantage by zip code: 10:22
  • Neighborhoods disadvantage and individual socioeconomic status: 13:17
  • Future research opportunities: 14:26
  • What can people in the community do with the results of this study? 17:36
  • Follow-up study: 18:23

COVID-19 Special Series The pandemic has placed a significant strain on the mental, social, and physical wellbeing of many caregivers, as well as individuals with cognitive decline. Our guest discusses COVID-19’s impact on underserved communities, offers communication tips, and reminds people to practice self-care. Guest: Andrea Gilmore-Bykovskyi, PhD, RN, University of Wisconsin-Madison School of Nursing 

Episode Topics: 

  • Caregiver considerations for a pandemic. 2:31
  • Self Care for caregivers. 6:05
  • How the pandemic is affecting caregivers from underserved communities. 10:55
  • Recommendations for caregivers when planning a trip to a medical facility. 13:51
  • Advice for families trying to communicate with loved ones who are hospitalized. 15:36
  • Tips for communicating with loved ones in a care facility. 17:43
  • What caregivers should know for the future. 21:05 

Show Notes: All of the important issues happening right now cannot be fully covered, so we strongly encourage you to go to trusted sources for specific information, such as the U.S. Centers for Disease Control and Prevention, your state and local health department websites, and the Alzheimer's Association. You can also find resources on our website, and that of the Wisconsin Alzheimer's Institute. For other interesting and important stories on the COVID-19 pandemic, I would recommend my colleague at UW Health Jonathan Kohler, MD, MA, of the Surgery Sett podcast who has a special series called The Frontlines of COVID.

COVID-19 Special Series Stress, fear, and anxiety are common responses to the uncertainty during the COVID-19 pandemic. However, with the regular practice of mindfulness, the meditative process of bringing your attention to your body in the present moment, has been seen to help calm the worry. Our guest joins us to discuss using mindfulness methods to maintain and mange an overall wellbeing. Guest: Vincent Minichiello, MD, University of Wisconsin School of Medicine and Public Health

Episode Topics:

  • How do you define mindfulness? 2:55
  • How does mindfulness affect our body? 5:15
  • Is it common to feel muscle relaxation while practicing mindfulness? 8:24
  • What are mindfulness-based interventions? 9:54  
  • Can mindfulness be health focused? 13:36
  • Where do you see mindfulness fitting into healthcare, especially during the pandemic? 14:01
  • How can mindfulness be useful during the COVID-19 pandemic? 16:11
  • Can mindfulness be beneficial for individuals with cognitive impairments and caregivers? 18:21
  • Where should you begin with a mindfulness practice? 20:20
  • How helpful are online or phone apps for mindfulness practices? 22:50
  • What are you doing to maintain your wellbeing during the COVID-19 pandemic? 25:18

Show Notes: For listeners local to Madison, the UW Health Mindfulness Program offers in-person classes. They have also expanded to online classes due to the pandemic. Another great resource is The Center for Healthy Minds at the University of Wisconsin–Madison. Apps our guest recommends are Mindfulness CoachCalmBuddhify and Headspace. A good starter book is Wherever You Go, There You Are by Jon Kabat-Zinn. All of the important issues happening right now cannot be fully covered, so we strongly encourage you to go to trusted sources for specific information, such as the U.S. Centers for Disease Control and Prevention, your state and local health department websites, and the Alzheimer's Association. You can also find resources on our website, and that of the Wisconsin Alzheimer's Institute. For other interesting and important stories on the COVID-19 pandemic, I would recommend my colleague at UW Health Jonathan Kohler, MD, MA, of the Surgery Sett podcast who has a special series called The Frontlines of COVID.

COVID-19 Special Series As a result of the COVID-19 pandemic visiting and communicating with people living with memory loss, whether at home or in a care facility, has become more difficult. Our guest joins us to outline the different ways to communicate remotely, how rural communities are adapting to this change and methods to help caregivers cope. Guest: Becky DeBuhr, MS, Program Director, Alzheimer’s & Dementia Alliance of Wisconsin.

Episode Topics:

  • Ways for caregivers to connect with loved one:o    Technology 3:02o    Window visits 4:41o    Mail 6:00
  • What can families reasonably ask of professional caregiving staff? 9:22
  • How can family members communicate their support remotely? 12:45
  • How are caregivers in rural communities being affected? Is there a difference in urban communities? 15:09
  • Methods to help caregivers cope now and post-pandemic. 17:40
  • Key tips for caregivers at home or in a facility. 20:21

Show Notes: To learn more about the Alzheimer’s & Dementia Alliance of Wisconsin call 888-308-6251 or email support@alzwisc.org. The Wisconsin Department of Health Services provides guidance for all long-term care facilities, assisted living facilities, and facilities serving people with developmental disabilities in Wisconsin caring for patients who are elderly and/or have chronic medical conditions that place them at higher risk of developing severe complications from COVID-19. All of the important issues happening right now cannot be fully covered, so we strongly encourage you to go to trusted sources for specific information, such as the U.S. Centers for Disease Control and Prevention, your state and local health department websites, and the Alzheimer's Association. You can also find resources on our website, and that of the Wisconsin Alzheimer's Institute. For other interesting and important stories on the COVID-19 pandemic, I would recommend my colleague at UW Health Jonathan Kohler, MD, MA, of the Surgery Sett podcast who has a special series called The Frontlines of COVID.

COVID-19 Special Series The field of telemedicine offers a diverse range of medical support services through telecommunication. Under the global pandemic, many providers have moved to telemedicine to assist their patients. Our guest discusses the advantages and disadvantages to using video and phone doctor visits and offers tips for best use of the services. Guest: Steve Barczi, MD, University of Wisconsin School of Medicine and Public Health

Episode Topics:

  • What is telemedicine? 3:25
  • Benefits of telemedicine 8:04
  • Downside of telemedicine? 11:05
  • Is telemedicine covered by insurance? 13:30  
  • How has COVID-19 changed the utilization of telemedicine? 18:27
  • Key takeaways 24:20
  • Telemedicine tips for people with cognitive impairments and older adults 25:05
  • How to prepare for a telemedicine visit 28:14
  • Best practices for a telemedicine visit 30:45

Show Notes: All of the important issues happening right now cannot be fully covered, so we strongly encourage you to go to trusted sources for specific information, such as the U.S. Centers for Disease Control and Prevention, your state and local health department websites, and the Alzheimer's Association. You can also find resources on our website, and that of the Wisconsin Alzheimer's Institute. For other interesting and important stories on the COVID-19 pandemic, I would recommend my colleague at UW Health Jonathan Kohler, MD, MA, of the Surgery Sett podcast who has a special series called The Frontlines of COVID.

COVID-19 Special Series This episode discusses the work done by The Alzheimer’s Association, an organization focused on providing community education and assistance to all affected by Alzheimer’s disease or other dementias. Our guest details how care and support services have quickly adapted to keep families and loved ones safe, healthy, and connected under quarantine. Guest: Kate Kahles, Program Manager, Alzheimer's Association Wisconsin Chapter

Episode Topics:

  • How have support groups changed under the pandemic? 2:53
  • Alzheimer’s Association Helpline 5:50
  • Types of support groups 7:15
  • Advice for coping with the anxiety from having a loved one in a facility 9:00
  • Outreach to rural communities 12:28 
  • How has the stay-at-home order affected caregivers? 13:49
  • Activities for caregivers and persons living with dementia 16:59
  • Advance care planning 19:24
  • Key services 20:14

Show Notes: To learn more about the Alzheimer’s Association and support services near you go to the Community Resource Finder or call the helpline at 1(800)272-3900. All of the important issues happening right now cannot be fully covered, so we strongly encourage you to go to trusted sources for specific information, such as the U.S. Centers for Disease Control and Prevention, your state and local health department websites. You can also find resources on our website, and that of the Wisconsin Alzheimer's Institute. For other interesting and important stories on the COVID-19 pandemic, I would recommend my colleague at UW Health Jonathan Kohler, MD, MA, of the Surgery Sett podcast who has a special series called The Frontlines of COVID.

 

COVID-19 Special Series The National Family Caregiver Support Program (NFCSP) offers information, support, and resources to assist family caregivers (spouse, adult child, other relative, friend or neighbor) with their concerns related to caregiving. COVID-19 has impacted many resources and supports. Funding is available to help. This episode delves into what the program offers and ways to support caregivers and care recipients especially during the pandemic Guest: Jane DeBroux, Caregiver Program Coordinator, Dane County Area Agency on Aging

Episode Topics:

  • What is the National Family Caregiver Support Program? 2:55 
  • How has the COVID-19 pandemic changed the program? 4:02
  • What does the program offer? 4:43
  • What are the eligibility requirements? 10:20

Show Notes: To learn more about the National Family Caregiver Support Program (NFCSP) program in your county reach out to your local Area Agency on Aging or Aging & Disability Resource Center. If in Dane County, Wisconsin, contact Jane DeBroux at (608) 261-5679. For all other Wisconsin counties go to wisconsincaregiver.org. All of the important issues happening right now cannot be fully covered, so we strongly encourage you to go to trusted sources for specific information, such as the U.S. Centers for Disease Control and Prevention, your state and local health department websites, and the Alzheimer's Association. You can also find resources on our website, and that of the Wisconsin Alzheimer's Institute. For other interesting and important stories on the COVID-19 pandemic, I would recommend my colleague at UW Health Jonathan Kohler, MD, MA, of the Surgery Sett podcast who has a special series called The Frontlines of COVID.

COVID-19 Special Series This episode continues our conversation with Art Walaszek, MD, focusing on the psychological and behavioral effects of the COVID-19 pandemic. Our guest helps us understand the fears and anxieties that are heightened during this time and recommendations to help best handle the increased stress. Guest: Art Walaszek, MD, Geriatric Psychiatrist, University of Wisconsin School of Medicine and Public Health

Episode Topics:

  • How do we handle our own fear during the pandemic? 6:00
  • What can you do to calm stress and anxiety before bed? 14:45
  • Do you have any specific recommendations for individuals with cognitive impairment or their caretakers facing increased anxiety? 23:51

Show Notes:  All of the important issues happening right now cannot be fully covered, so we strongly encourage you to go to trusted sources for specific information, such as the U.S. Centers for Disease Control and Prevention, your state and local health department websites, and the Alzheimer's Association. You can also find resources on our website and that of the Wisconsin Alzheimer's Institute. For other interesting and important stories on the COVID-19 pandemic, I would recommend my colleague at UW Health Jonathan Kohler, MD, of the Surgery Sett podcast who has a special series called "The Frontlines of COVID."

COVID-19 Special Series This episode begins our pivot to addressing the important issues facing individuals during the current COVID-19 pandemic. We will speak to researchers and doctors discussing the present and future impact of the pandemic on those with cognitive impairment and those without. We are starting with a two-part series on the psychological and behavioral consequences of the pandemic. Our guest, Art Walaszek, MD, speaks on the effects of social distancing and how individuals or caregivers can stay healthy during this time. Guest: Art Walaszek, MD, Geriatric Psychiatrist, University of Wisconsin School of Medicine and Public Health

Episode Topics:

  • Does social distancing negatively affect you? 5:00
  • How does this affect individuals with cognitive impairment or their caregivers? 11:00
  • What can we all do to prevent any negative effects from social distancing? 15:30

Show Notes:  All of the important issues happening right now cannot be fully covered, so we strongly encourage you to go to trusted sources for specific information, such as the U.S. Centers for Disease Control and Prevention, your state and local health department websites, and the Alzheimer's Association. You can also find resources on our website and that of the Wisconsin Alzheimer's Institute. For other interesting and important stories on the COVID-19 pandemic, I would recommend my colleague at UW Health Jonathan Kohler, MD, of the Surgery Sett podcast who has a special series called "The Frontlines of COVID."

This episode offers an overview of the current tools doctors use to examine Alzheimer’s disease risk in their patients, as well as new techniques in development. Our guest discusses the science behind risk testing for dementia, as well as the potential for a low-cost risk test. Guest: Sanjay Asthana, MD, associate dean for gerontology at the University of Wisconsin School of Medicine and Public Health and director at the Wisconsin Alzheimer’s Disease Research Center 

Episode Topics:

  • What are the current tools that doctors have for understanding risk for dementia? 0:52
  • Memory clinic patient experience: 3:02
  • What is the difference between risk scores and calculators? 6:16
  • Genetic testing: 7:29
  • Risk and interventions for a diverse population: 13:17
  • How close is a low-cost risk test? 17:39
  • What do you do to reduce your risk for developing Alzheimer’s disease? 19:12

This episode explores genetic risk factors for early- and late-onset Alzheimer’s disease. Host Nathaniel Chin and guest Corinne Engelman discuss the research looking into genetic risk for Alzheimer’s disease and the uncertainty that comes with genetic testing. Guest: Corinne Engelman, MSHP, PhD, associate professor, Department of Population Health Sciences, University of Wisconsin School of Medicine and Public Health

Episode Topics:

  • What are the genetic influences on a person’s risk for Alzheimer’s disease? 2:07
  • What genes affect individuals with early-onset dementia? 2:56
  • What is the impact of genes that counter one another? 5:34
  • How much can our lifestyle choices affect our genetic risk? 7:52
  • How is the genetic testing being analyzed? 9:03 
  • What can at-home genetic testing tell us about Alzheimer’s disease? 10:06
  • How essential is the role of genetic counselor? 11:47
  • Have we found any genetic risks related to the aging process? 13:21
  • What advice do you have for people interested in maximizing their genetic outcome when it comes to Alzheimer's disease risk? 14:40 

Our guest, Dr. Kimberly Mueller, joins us to discuss cognitively stimulating activities and the impact of social engagement on brain health. Guest: Kimberly Mueller, PhD, CCC-SLP, Assistant Professor, Department of Communications Sciences and Disorders, University of Wisconsin-Madison

Episode Topics:

  • What are cognitively stimulating activities? 1:25
  • Recent studies: 2:50
  • Are some activities better than others? 9:00
  • Are Jeopardy or other “active” television shows considered cognitively stimulating? 10:23
  • Are board games, crossword puzzles, and brain games considered cognitively stimulating activities? 11:22
  • Is there evidence showing the benefits of social engagement? 15:08
  • Advice for maintaining and strengthening brain health: 18:37

In this bonus episode, we continue our conversation with Dr. Howie Rosen on Frontotemporal Dementia (FTD). On last week’s episode, Dr. Rosen spoke on the genetic risk factors, trajectories and family caregiving experiences of FTD. Now, our conversation turns to the research looking into how the disease affects self-awareness, biomarkers and early detection, as well as ways people can volunteer for a research study. Guest: Howard “Howie” Rosen, MD, behavioral neurologist at the University of California San Francisco Memory and Aging Center

Episode Topics:

  •         FTD and self-awareness: 1:10
  •         Research into biomarkers for Frontotemporal Dementia: 4:42
  •         How can people help the research: 11:40

Frontotemporal dementia (FTD) is a type of dementia caused by degeneration in the temporal and frontal lobes of the brain. Our guest discusses the symptoms, risk factors, prevalence, and course of the disease, along with information on how a doctor diagnoses FTD and what families and caregivers can do after diagnosis. Guest: Howard “Howie” Rosen, MD, behavioral neurologist at the University of California San Francisco Memory and Aging Center

Episode Topics:

A definition of Frontotemporal Dementia (FTD) 1:02

How common is FTD? 3:53

Genetic risk factors of FTD: 4:30

Non-genetic risk factors of FTD: 6:40

Symptoms of FTD: 8:40

How a clinician diagnoses FTD: 14:03

What is the course of the disease? 16:20

What to do after a diagnosis: 18:51

Family and caregiver experience of FTD: 22:36

Community support and networking: 25:53

Our guests, Dr. Rebecca Koscik and Dr. Tobey Betthauser, are researchers investigating the trajectory of amyloid and tau proteins over time and the significance of amyloid chronicity. Koscik and Betthauser discuss their two recent publications on the topic and how amyloid PET scans have helped scientists better understand the early brain changes associated with Alzheimer’s disease. Guests: Rebecca Koscik, PhD, senior scientist, Tobey Betthauser, PhD, postdoctoral fellow, University of Wisconsin-Madison

In this episode, we discuss ...

  • How amyloid PET tracers work 7:17
  • Published research on amyloid duration 12:01
  • Research supporting amyloid chronicity 18:14

Our guest is Dr. Sterling Johnson, associate director of the Wisconsin Alzheimer’s Disease Research Center and principal investigator of the Wisconsin Registry for Alzheimer's Prevention (WRAP) study at the University of Wisconsin-Madison. The WRAP study is one of the largest and longest-running observational studies of Alzheimer's disease in the world. Dr. Johnson shares study findings, discusses advancements in brain imaging, and introduces the concept of amyloid chronicity. Guest: Sterling Johnson, PhD, professor of medicine (geriatrics), University of Wisconsin School of Medicine and Public Health

Show Notes:

  • What is the WRAP study? 3:28
  • Findings from the study: 8:06
  • WRAP studies outside of Wisconsin: 10:59
  • What is amyloid chronicity? 15:19

 

Dr. J. Neil Henderson is an expert on diabetes and dementia, as well as creating culturally specific caregiver training programs for people who care for American Indian elders. Dr. Henderson, who is Oklahoma Choctaw, discusses cultural influences on caregiving and his work in improving brain health among American Indians and rural populations. Guest: J. Neil Henderson, PhD, professor, University of Minnesota School of Medicine, Duluth campus; executive director, Memory Keepers Medical Discovery Team on Health Disparities

Show Notes:

  • Trainable caregiving skills: 1:07

  • Impact of culture on caregiving: 6:29

  • American Indian and rural health disparities in memory: 10:35