Untreated hearing loss can make it harder to connect with family and friends or navigate daily life. When we can’t hear clearly, we rely on our brains more to fill in the missing pieces. Even a mild hearing loss may mean our brain is working harder. New laws have made hearing aids available for purchase over-the-counter (OTC) if someone has a mild to moderate hearing loss. We want to know if OTC hearing aids are beneficial to listeners with changes to their thinking and memory skills.
The Wisconsin Alzheimer’s Disease Research Center (ADRC) and the Wisconsin Registry for Alzheimer’s Prevention (WRAP) at the University of Wisconsin-Madison are conducting a brain imaging research study to identify how Alzheimer’s disease develops. We use positron emission tomography (PET) to image amyloid plaques and neurofibrillary tangles.
Help us learn why dementia affects Black Americans at higher rates than other groups.
The Wisconsin ADRC is joining centers around the nation to conduct a brain imaging research study to identify how Alzheimer’s disease and related dementias develop. We use positron emission tomography (PET) to image amyloid plaques and tau tangles in the brain.
The purpose of the Wisconsin Alzheimer's Disease Research Center (ADRC) Clinical Core is to help researchers identify people at risk for Alzheimer’s disease earlier and find better ways to prevent and treat Alzheimer’s disease and related memory disorders. People who join the Clinical Core attend either annual or every-other-year visits with a study partner and undergo memory and thinking abilities evaluations.
The DEMENTIA CAre and Caregiving RESearch Registry study is a registry to help connect people to research opportunities on care and caregiving.
This study aims to look at the unique gut microbiomes of women, their biological children and/or their domestic partners to determine whether parental family history and co-habitant exposure shapes the gut microbiome and Alzheimer's disease (AD) outcomes. Differences between microbiomes discovered in this investigation could help treat and diagnose Alzheimer’s disease.
The KLOTHO study helps us further understand aging by looking at a gene, called KLOTHO, that may play a role in brain health.
This study will try to see if performing tongue press exercises and using a saliva substitute improve swallowing ability in patients with memory problems and dysphagia.
LUCINDA is a clinical research trial to determine whether leuprolide (Eligard, an injectable medication) can slow or prevent decline in thinking abilities and functioning in women with mild cognitive impairment (MCI) or Alzheimer’s disease who are also taking a cholinesterase inhibitor medication such as donepezil.
The MARS: Microbiome in Alzheimer’s Risk Study at the University of Wisconsin investigates the impact of human gut microbes on the development of Alzheimer’s disease. Differences between microbiomes discovered in this investigation would provide researchers with risk factors that can help diagnose and treat Alzheimer’s.
PREVENTABLE is a pragmatic evaluation of events and benefits of lipid-lowering in older adults. This is one of the largest research studies for older adults taking place at 100 locations across the country. The William S. Middleton Memorial Veterans’ Hospital is one of the PREVENTABLE sites looking to partner with people 75 years or older to learn if taking a statin could help older adults live well for longer by preventing dementia, disability, or heart disease. A statin is a commonly used drug to lower cholesterol.
New studies start frequently at the Wisconsin ADRC, and we're looking for men and women volunteers. In order to match interested persons with future studies, the Wisconsin ADRC has created a research database — the Wisconsin ADRC Research Recruitment Registry — to hold the names and eligibility information of potential volunteers. When new studies become available, we will use the Wisconsin ADRC Registry to identify persons who may qualify for the new opportunity.
Dr. Megan Gilligan and The Families in Later Life Research Lab at Iowa State University are conducting a study to better understand the role of family dynamics in the health and well-being of adult children who provide care to a parent with Alzheimer’s disease or related dementia (ADRD).
The goal of the SPEAK-AD study is to validate changes in speech as a measure of cognition in individuals at increased risk of Alzheimer’s disease and related dementias (ADRD). We will achieve this by inviting WRAP and ADRC participants to perform at-home speech tasks on a mobile application.
The Synaptic Therapy Alzheimer’s Research Trial (START) is a national study funded by the National Institute on Aging (NIA) of the National Institutes of Health (NIH). Through the START study, researchers seek to learn if a new drug treatment taken orally, called CT1812, can safely slow memory loss caused by Alzheimer’s disease.
By our definition, SuperAgers are adults over age 80 who have the memory capacity of individuals who are at least three decades younger. Studying SuperAgers is important to understand what is going right with aging, as opposed to what is going wrong. The SuperAging program helps us identify those protective factors that contribute to remarkable memory performance in late life, including genetic, lifestyle and brain factors (such as what is found in the brain after death).
The purpose of the study is to learn whether a new smartphone test called the Assessment of Smartphone Everyday Tasks (ASSET) can help doctors make an early diagnosis of Alzheimer’s disease and track early changes in daily functioning.
UW–Madison Pulmonary Research and The Center for Healthy Minds are looking for participants for a study to help us better understand the relationship between airway inflammation and the brain.
UW–Madison Department of Ophthalmology and Visual Sciences is conducting a study to find out if an investigational smell test and eye images can be used to screen for Alzheimer’s disease.
