The AHEAD Study is the first research study that aims to help prevent Alzheimer’s disease by enrolling participants as young as 55 and using a tailored dosing approach.
The Wisconsin Alzheimer’s Disease Research Center (ADRC) and the Wisconsin Registry for Alzheimer’s Prevention (WRAP) at the University of Wisconsin-Madison are conducting a brain imaging research study to identify how Alzheimer’s disease develops. We use positron emission tomography (PET) to image amyloid plaques and neurofibrillary tangles.
A new study, ARMADA: Advancing Reliable Measurement in Alzheimer’s Disease and Cognitive Aging, will test a new set of measures on the iPad to determine whether they can detect early signs of cognitive decline.
The goal of the BRAVE study is to find out if a purified form of fish oil can stop or delay early brain changes associated with Alzheimer's disease in middle-aged, cognitively healthy Veterans at risk for this common form of dementia.
Help us learn why dementia affects Black Americans at higher rates than other groups.
The purpose of the Wisconsin Alzheimer's Disease Research Center (ADRC) Clinical Core is to help researchers identify people at risk for Alzheimer’s disease earlier and find better ways to prevent and treat Alzheimer’s disease and related memory disorders. People who join the Clinical Core attend either annual or every-other-year visits with a study partner and undergo memory and thinking abilities evaluations.
The Dementia Care Research Core Recruitment Registry is a new opportunity for both people with memory problems and their caregivers. Care research focuses on understanding how to improve the quality of life for people with Alzheimer’s disease and their families by looking at the care they receive (at home or within the healthcare system).
This unique study is a continuation of the original LEAD study. We will collect brain imaging scans, cerebral spinal fluid and blood to measure changes in the brain and specifically learn more about brain white matter. We will evaluate how degeneration of white matter plays a critical role in Alzheimer’s disease progression as well as develop methods to properly measure changes in brain white matter.
This study will try to see if performing tongue press exercises and using a saliva substitute improve swallowing ability in patients with memory problems and dysphagia.
The LIFE study is investigating the effects of aerobic fitness and physical activity over time to better understand how those factors might help to promote healthy brain aging and delay the onset of clinical symptoms of Alzheimer's disease in the future.
PREVENTABLE is a pragmatic evaluation of events and benefits of lipid-lowering in older adults. This is one of the largest research studies for older adults taking place at 100 locations across the country. The William S. Middleton Memorial Veterans’ Hospital is one of the PREVENTABLE sites looking to partner with people 75 years or older to learn if taking a statin could help older adults live well for longer by preventing dementia, disability, or heart disease. A statin is a commonly used drug to lower cholesterol.
New studies start frequently at the Wisconsin ADRC, and we're looking for men and women volunteers. In order to match interested persons with future studies, the Wisconsin ADRC has created a research database — the Wisconsin ADRC Research Recruitment Registry — to hold the names and eligibility information of potential volunteers. When new studies become available, we will use the Wisconsin ADRC Registry to identify persons who may qualify for the new opportunity.
This unique study uses positron emission tomography (PET) brain scans to visualize neuronal synapse density, amyloid plaques and neurofibrillary tangles. We will also obtain MRI data to investigate how these factors are affecting brain health. The study examines whether Alzheimer's disease pathology affects the quantity of synapses, and whether loss of synapses over time is associated with cognitive decline.
