GUT-LUV Study: The Loved Ones Unite to Investigate Familial Microbial Transfer Pilot Study

This study aims to look at the unique gut microbiomes of women, their biological children and/or their domestic partners to determine whether parental family history and co-habitant exposure shapes the gut microbiome and Alzheimer's disease (AD) outcomes.

Study goal

Better understand how the gut microbiome may influence brain aging and disease risk in AD among cohabitants and offspring.

What is the gut microbiome?

Human bodies are made up of a combination of human cells and microbial cells (including fungi and bacteria). The largest population of microbes in the human body is contained in the gut. These microbes, known as the “gut microbiome”, affect our body and health in various ways.

Who can participate?

We are looking to enroll family groups that include a female participant with cognitive impairment and either their cohabitant and/or their biological children.

Participation Eligibility

Specific requirements include:

Female study participants
- Must 60 years old or older
- MCI or AD diagnosis
Biological children
- 55 years of age or older
- Does not currently live with the female participant
Cohabitants adults
- Reside with the female participant
- Preferably spouses or romantic partners
- 55 years of age or older

What will I be asked to do?

Participants will be asked to complete:

A stool sample collection kit
A blood collection card (optional)
Diet and lifestyle questionnaires
Cognitive testing

Where will I complete this study?

This is a remote study. You will complete the entire study in the comfort of your own home. All procedures are done via mail and by phone.

Will I be paid for participating in this study?

Yes, you will be paid for participating.

$75 for the stool sample
$25 for the blood spot

There is no cost to you for being in the study.

What if I change my mind?

Participation in this study is voluntary. You can stop participating at any time.

Contributing to a better future

The contribution you are making by participating in research is long-lasting and far-reaching, with the goal of helping future generations. This particular study may uncover better ways to prevent and slow Alzheimer’s disease. Thank you for your interest in this and other studies!