SPEAK-AD study

The goal of the SPEAK-AD study is to validate changes in speech as a measure of cognition in individuals at increased risk of Alzheimer’s disease and related dementias (ADRD). We will achieve this by inviting WRAP and ADRC participants to perform at-home speech tasks on a mobile application. The mobile application will record the participants’ speech as they complete the tasks, so it can be analyzed by speech and language researchers. 

It is important to investigate speech and language because these have shown associations with cognitive decline and Alzheimer’s disease biomarkers. This study will clarify how speech may be affected by Alzheimer’s disease and may help us predict the likelihood that someone will develop dementia. 

Study Commitment and Compensation

• Annual at-home speech collection sessions for 3 years
  • Each year an 8-week at-home speech collection period will be completed
  • One, 30-minute at-home speech collection session will be completed weekly for 8 consecutive weeks
  • At the end of the 8-week at-home speech collection period, there will be a brief survey
• Speech collection sessions will take place remotely, in the comfort of your own home
• All participants will be provided with an iPad to complete study procedures, which they will keep upon study completion as compensation
• Internet access is not required for participation